Epigenetics in Cancer Original PDF  

 As the second leading cause of death, cancer has cast an overwhelming shadow on millions of lives worldwide. Everyone is affected in some way, if not by having the disease themselves, then by witnessing it in friends or loved ones.Epigenetics is a rapidly-growing field and a fascinating area of cancer research. The book addresses the importance of fighting cancers with an epigenetics approach. Specifically, the following topics are reviewed:• (1) DNA methylation and cancer.• (2) Non-coding RNAs in cancer.• (3) Epigenetics in the diagnosis, prognosis, and therapy of cancer.• (4) Epigenetic effects of environmental and dietary factors in cancer.The book also includes a chapter that provides short but practical protocols widely used in epigenetics research. Finally, it provides insight into future directions in cancer epigenetics research.Thus, this book covers a wide range of topics, from general mechanisms of cancer epigenetics to cancer therapy. This book will be helpful to improve the understanding of epigenetics and cancer who are interested in cancer epigenetics and the development of anticancer drugs at various levels, including students in medical and biological fields, postdoctoral fellows, university researchers, and/or educators.Table of Contents• Overview of Epigenetics• DNA Methylation and Cancer• Non-coding RNA’s in Cancer• Chromatin Remodeling and Cancer• Epigenetic Therapy of Cancer-From Mechanisms to Clinical Utility• Epigenetic Effects of Environmental and Dietary Factors in Cancer Development and Bioethical Implications• Main Protocols in Cancer Epigenetics.