Targeted Protein Degradation Methods and Protocols 2021 Original pdf+videos

Targeted Protein Degradation Methods and Protocols 2021 Original pdf+videos

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AUTHORS: Angela M. Cacace Christopher M. Hickey Miklós Békés
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Targeted Protein Degradation Methods and Protocols 2021 Original pdf+videos

This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

 

Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

AUTHORS: Angela M. Cacace Christopher M. Hickey Miklós Békés

PAGES: 351

YEAR: 2021

PUBLICATION: Humana, New York, NY

LANGUAGE: English

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